Preprint Highlights

23 juli 2025

Mitochondrial proteins go public and novel interactions: insights from surfaceome mapping

Adam J. Grippin & Wen Jiang

17 juli 2025

BRD4 acts as a pH sensor to tune inflammation

Siu Ling Tai & Arthur Mortha

7 juli 2025

Spatial immunometabolic zonation in tuberculosis granulomas

Amitava Sinha & Thomas Weichhart

1 juli 2025

Tumour cells mimic erythroblasts to hijack iron from bone marrow macrophages

Mehdi Chaib & James P. Allison

25 juni 2025

Insulin neoantigen elicits memory T cell activation in diabetes

Boyan K. Tsankov & Dana J. Philpott

12 juni 2025

Gut ILC2s remember IL-25

Brian Y. Soong & Miriam Merad

12 juni 2025

Uncovering the hidden landscape of tumour antigens

Benjamin R. Schrank & Betty Y. S. Kim

2 juni 2025

Fetal Treg cell reprogramming links maternal immunity to neurodevelopment

Mahdieh Golzari-Sorkheh & Juan Carlos Zúñiga-Pflücke

21 maj 2025

Releasing the brakes on phagosomes

John Benjamin W. Duncan & Kelsey Voss

6 maj 2025

Progenitor exhausted T cells contribute to the formation of immunological memory

Annette Wu & Wen Jiang

23 apr. 2025

Monocytes rule energy metabolism with an iron fist

Felix Clemens Richter & Kelsey Voss

23 apr. 2025

CDKN2Alow tumours mediate immunotherapy resistance by depriving macrophages of zinc

Robbie Jin & Tracy L. McGaha

28 mars 2025

Resident tissue macrophages maintain intraocular pressure by regulating extracellular matrix homeostasis

Alex Lac & Slava Epelman

28 mars 2025

Macrophages promote nerve growth in both tumours and spinal cord

Austeja Baleviciute & Sebastien Talbot

27 mars 2025

Early antiviral type I interferon impairs lung metastasis

Lisha Jeena & Ester Gea-Mallorquí

5 mars 2025

Neutrophils are dispensable for Shigella control: macrophages take centre stage

Didem Ağaç Çobanoğlu & James P. Allison

5 mars 2025

Mapping the developmental trajectory and recruitment of memory-phenotype Ly49+CD8+ T cells

Guillaume J. Trusz & Verena van der Heide

3 mars 2025

Type 1 immune response reduces seizure risk after traumatic brain injury

Jennifer S. Y. Ahn & Jennifer L. Gommerman

31 jan. 2025

Podoplanin mediates stromal–immune crosstalk in the lymph node

Erika E. McCartney & Matthew B. Buechler

8 jan. 2025

In vivo enhancement of tumour-specific T cells via peptide–MHC-pseudotyped retroviral gene delivery

Hugo Kwong & Persephone Borrow

9 dec. 2024

Systematic identification of cell state-specific transcription factors in T cells

Didem Ağaç Çobanoğlu

26 nov. 2024

Mitochondria in monocyte-derived cells promote tissue damage in multiple sclerosis

Zi Yan Chen & Arthur Mortha

25 nov. 2024

Redefining PD1 as a guardian of stem-like T cells

Matthew Jackson & Eileen E. Parkes

4 juli 2024

Rethinking pDCs: a questionable ally in immunity?

Ester Gea-Mallorquí & Sarah Rowland-Jones

4 juli 2024

Microbiota licenses protective CD8+ T cell responses against neonatal influenza

Boyan K. Tsankov & Dana J. Philpott

2 juli 2024

Actin branching maintains tissue-resident mast cells

Louis Ngai & Arthur Mortha

24 maj 2024

Breast cancer-associated fibroblasts maintain self-renewing immunosuppressive macrophages

Anthony Altieri & Matthew B. Buechler

26 apr. 2024

FAS signalling pathway is crucial for CAR T cell persistence

Robyn Loves & Eyal Grunebaum

22 apr. 2024

Oxidized phospholipids during microbial challenge: friend or foe?

Henrique G. Colaço & Kelsey Voss

8 mars 2024

Getting under the skin: resident memory CD8+ T cells have a second residence in the draining lymph node

Teresa Neuwirth, Azuah L. Gonzalez, Emilie Fisher-Gupta & Georg Stary

6 mars 2024

Lymph node resection does not impair cancer immunotherapy responses

Lucas Baldran-Groves & Jeroen Melief

1 mars 2024

Pre-existing antibody allows for maturation of new B cells in ‘recall’ germinal centres

Jake Herb & Maria Curotto de Lafaille

10 feb. 2024

Navigating the thymic landscape through development: from cellular atlas to tissue cartography

Dörte Symmank, Felix Clemens Richter & André F. Rendeiro

30 jan. 2024

Clonal haematopoiesis-associated, age-related motor deficits caused by monocyte-derived microglia

Austeja Baleviciute & Lily Keane

22 jan. 2024

Take my breath away—mitochondrial dysfunction drives CD8+ T cell exhaustion

Felix Clemens Richter, Mariia Saliutina, Ahmed N. Hegazy & Andreas Bergthaler

20 jan. 2024

Same name, different game?—How ontogeny shapes classical monocyte phenotypes

Lisabeth Pimenov, Azuah Lucrecia Gonzalez, Amanda C. Doran & Sylvia Knapp

12 jan. 2024

Alternative RNA splicing generates shared clonal neoantigens across different types of cancer

Matthew Brown & Nicolas Vabret

6 dec. 2023

Adipose tissue maintains healthy joint fibroblasts via cortisol signalling

Micon Garvilles & Mark Coles

6 dec. 2023

TCRs and AI: the future is now

Malcolm J. W. Sim

4 dec. 2023

Neonatal monocytes suppress adult TH17 cell responses in skin

Siu Ling Tai & Arthur Mortha

26 juli 2023

Heterologous immunity: innate function of memory CD4+ T cells

Mariana Borsa & Carmen Gerlach

25 juli 2023

Re-investigating the origin and fates of colonic Treg cell subsets

Kyle Burrows & Arthur Mortha

3 juli 2023

Pannexin 1 regulates CD8+ T cell function and memory formation

Mireia Cruz De Los Santos & Andreas Lundqvist

29 juni 2023

The kiss a cell can’t forget: tracking cell–cell interactions with uLIPSTIC

Yavuz F. Yazicioglu & Alexander J. Clarke

27 juni 2023

Adventitial fibroblast–ILC2 niche restrains liver fibrosis

Anthony Altieri & Matthew B. Buechler

26 maj 2023

A skull bone marrow niche for antitumour neutrophils in glioblastoma

Austeja Baleviciute & Lily Keane

9 maj 2023

Pancreatitis points to key role of dendritic cells in pancreatic cancer

Lucas Baldran-Groves & Jeroen Melief

3 maj 2023

Perforin 2 mediates endosomal antigen export for cross-presentation

Aljawharah Alrubayyi & Sarah Rowland-Jones

29 mars 2023

Adaptive meets innate: CD8+ T cells kill MHC-I-negative tumour cells

Bas W. A. Peeters & Geraldine M. Gillespie

23 mars 2023

Reservoirs of allergic memory

Michelle Tran & Cecilia Berin

6 mars 2023

Linking the maternal milk microbiota and infant respiratory infections

Lily Keane & Rochellys Diaz Heijtz

2 mars 2023

Human T follicular regulatory cells with helper and regulatory lineage origins

Quang Nguyen & Persephone Borrow

3 feb. 2023

MHCing the tumour’s dark genome

Miriam Saffern & Robert Samstein

3 jan. 2023

Sex-specific role for microglial CST7 in Alzheimer’s disease

Austeja Baleviciute & Lily Keane

3 jan. 2023

STAT5A antagonizes TOX in CD8+ T cell exhaustion

David Arcia-Anaya & Tim Elliott

24 nov. 2022

Tumour antigen spreading mediated by vaccine-boosted CAR T cells

Jaime Mateus-Tique & Brian Brown

31 okt. 2022

Dynamics of antigen retention by follicular dendritic cells

Nicolas Ruffin & Ester Gea-Mallorquí

22 juli 2022

XXtra killer cells

Ashley Reid Cahn & Adam M. Farkas

22 juli 2022

Tissue-specific epigenomics of resident memory CD8+ T cells

Thi My Hanh Luong & Marcus Buggert

19 maj 2022

The CD58–CD2 axis in cancer immune evasion

Max Quastel & Michael Dustin

29 apr. 2022

Comparative immunology reveals different flavours of cGAS

Bethany Charlton & Ester Gea-Mallorquí

28 apr. 2022

The two faces of pancreas tissue-resident macrophages

Miriam Saffern & Miriam Merad

2 mars 2022

ILC3-induced regulatory T cells are directed by gut microorganisms

Rahul Ravindran & Emily Thornton

22 feb. 2022

Exhausted T cell phenotypes depend on TCR signal strength

Michelle A. Tran & Nina Bhardwaj

27 jan. 2022

Harnessing CXCL13 in ovarian cancer

Elena Brenna & Isabela Pedroza-Pacheco

26 jan. 2022

Omicron entry route

Luisanna Pia & Sarah Rowland-Jones

15 dec. 2021

A pan-cancer signature for dysfunctional T cells

Nicolas Ruffin & Andre Ortlieb Guerreiro-Cacais

18 nov. 2021

Macrophage commonalities across tissues and inflammation

Felix Clemens Richter & Irina Udalova

17 nov. 2021

Not just neighbours: positive feedback between tumour-associated macrophages and exhausted T cells

Gabrielle S. Lubitz & Joshua D. Brody

27 okt. 2021

Repeat elements amplify TLR signaling

Timothy O’Donnell & Nicolas Vabret

8 juni 2021

Rather active for ‘exhausted’ T cells

Julie M. Mazet & Anne Chauveau

8 juni 2021

Exhausted T cells never fully recover

Ashley Reid & Etienne Humblin

12 maj 2021

NK cells seize PD1 from leukaemia cells

Jenna Newman & Amir Horowitz

12 maj 2021

Cooperation between the alveolar epithelium and lung-resident basophils shapes alveolar macrophages

Matthew D. Park & Miriam Merad

14 apr. 2021

Innate IL-13 licenses dermal type 2 dendritic cells for efficient T helper 2 cell responses

Raphaël Mattiuz & Miriam Merad

14 apr. 2021

Seeing SARS-CoV-2 variants through the eyes of T cells

Aljawharah Alrubayyi & Dimitra Peppa

9 mars 2021

Maternal infection programmes offspring immunity

Nelson M. LaMarche & Jeremiah J. Faith

9 mars 2021

One carbon (metabolism) to rule T cell identity

Felix Clemens Richter & Alexander J. Clarke

10 feb. 2021

Targeting autoantibodies in COVID-19

Isabela Pedroza-Pacheco & Persephone Borrow

10 feb. 2021

Taking CAR T cells up a synthetic Notch

Miriam Saffern & Robert Samstein

11 jan. 2021

Sensing our Z-RNA

Ester Gea-Mallorquí & Sarah Rowland-Jones

11 jan. 2021

Super(antigen) target for SARS-CoV-2

Matthew Brown & Nina Bhardwaj

9 apr. 2020