Latest Preprints
1 dec. 2020
Vaccination reshapes the virus-specific T cell repertoire in unexposed adults
Pan*, Aiamkitsumrit* et al. (BioRxiv)
1 jan. 2021
A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro
Cheng, M.H. et al. (BioRxiv)
2 jan. 2021
Multi-antigen recognition circuits overcome challenges of specificity, heterogeneity, and durability in T cell therapy for glioblastoma
Choe J.H. et al. (BioRxiv)
3 jan. 2021
Neoantigen driven B cell and CD4+ T follicular helper cell collaboration promotes robust anti-tumor CD8+ T cell responses
Cui C. et al. (BioRxiv)
4 jan. 2021
ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation
De Reuver et al. (BioRxiv)
5 jan. 2021
Skin-resident immune cells actively coordinate their distribution with epidermal cells during homeostasis
Park S. et al. (MedRxiv)
6 jan. 2021
Diverse Functional Autoantibodies in Patients with COVID-19
Wang E.Y. et al. (MedRxiv)
1 feb. 2021
Combining an alarmin HMGN1 peptide with PD-L1 blockade facilitates stem-like CD8+ T cell expansion and results in robust anti-tumor effects
Chen C.-Y. et al. (BioRxiv)
2 feb. 2021
A reservoir of stem-like CD8 T cells in the tumor-draining lymph node maintains the ongoing anti-tumor immune response
Connolly K.A. et al. (BioRxiv)
3 feb. 2021
Novel gut pathobionts confound results in a widely used model of human inflammatory disease
Forster S.C. et al. (BioRxiv)
4 feb. 2021
Maternal infection promotes offspring tissue-specific immune fitness
Lim A.I. et al. (BioRxiv)
5 feb. 2021
Altered basal lipid metabolism underlies the functional impairment of naive CD8+ T cells in elderly humans
Nicoli F. et al. (BioRxiv)
6 feb. 2021
MTHFD2 is a Metabolic Checkpoint Controlling Effector and Regulatory T Cell Fate and Function
Sugiura A. et al. (BioRxiv)
1 mars 2021
Murine ex vivo cultured alveolar macrophages provide a novel tool to study tissue-resident macrophage behavior and function
Gorki A.-D. et al. (BioRxiv)
2 mars 2021
The skin environment controls local dendritic cell differentiation and function through innate IL-13
Mayer J.U. et al. (BioRxiv) DOI: 10.1101/2021.01.05.425466
3 mars 2021
Negligible impact of SARS-CoV-2 variants on CD4+ and CD8+ T cell reactivity in COVID-19 exposed donors and vaccinees
Tarke A. et al. (BioRxiv) DOI: 10.1101/2021.02.27.433180
4 mars 2021
Sting orchestrates the crosstalk between polyunsaturated fatty acids metabolism and inflammatory responses
Vila I.K. et al. (BioRxiv) DOI: 10.1101/2020.12.22.423950
5 mars 2021
CINS: Cell Interaction Network inference from Single cell expression data
Yuan Y. et al. (BioRxiv) DOI: 10.1101/2021.02.22.432206
1 apr. 2021
Alveolar macrophages strictly rely on GM-CSF from alveolar epithelial type 2 cells before and after birth
Gschwend J. et al. (BioRxiv) DOI: 10.1101/2021.04.01.438051
2 apr. 2021
When killers become thieves: trogocytosed PD-1 inhibits NK cells in cancer
Hasim M.S. et al. (BioRxiv)
3 apr. 2021
Extracellular Delivery of Functional Mitochondria Reverses the Dysfunction of CD4+ T Cells in Aging
Headley C.A. et al. (BioRxiv)
1 maj 2021
Hematopoietic stem cell requirement for macrophage regeneration is tissue-specific
Eddins D.J. et al. (BioRxiv)
2 maj 2021
The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair
McCowan J. et al. (BioRxiv)
3 maj 2021
Differentiation of exhausted CD8 T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory
Tonnerre P et al. (BioRxiv)
4 maj 2021
Active Surveillance Characterizes Human Intratumoral T Cell Exhaustion
You R. et al. (BioRxiv)
1 juni 2021
Signatures of mast cell activation are associated with severe COVID-19
Tan J., Anderson D.E. et al. (MedRxiv)
2 juni 2021
The extracellular ATP receptor P2RX7 imprints a pro-memory transcriptional signature in effector CD8+ T cells
Vardam-Kaur T. et al. (BioRxiv)
1 sep. 2021
Excess dietary sugar impairs colonic epithelial regeneration 1 in response to damage
Burr A.H.P. et al. (BioRxiv)
2 sep. 2021
SARS-CoV-2 mRNA vaccination elicits robust and persistent T follicular helper cell response in humans
Mudd P.A. et al. (BioRxiv)
3 sep. 2021
Induction of transposable element expression is central to innate sensing
Rookhuizen D.C. et al. (BioRxiv)
1 okt. 2021
Hematopoietic stem and progenitor cells integrate Bacteroides-derived innate immune signals to promote gut tissue repair
Hayashi Y. et al. (BioRxiv)
2 okt. 2021
Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer
Kersten K. et al. (BioRxiv)
3 okt. 2021
Predictive framework of macrophage activation
Sanin D.E. et al. (BioRxiv)
1 nov. 2021
Pan-cancer mapping of single T cell profiles reveals a TCF1:CXCR6-CXCL16 regulatory axis essential for effective anti-tumor immunity
Jerby-Arnon L. et al. (BioRxiv)
2 nov. 2021
Microbiome-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer
Overacre-Delgoffe A.E. et al. (BioRxiv)
3 nov. 2021
Commensal bacteria promote type I interferon signalling to maintain immune tolerance
Vasques Ayala A. et al. (BioRxiv)
1 dec. 2021
γδ T cells are effectors of immune checkpoint blockade in mismatch repair-deficient colon cancers with antigen presentation defects
de Vries N.L. et al. (BioRxiv)
2 dec. 2021
Antigen presentation by type 3 innate lymphoid cells instructs the differentiation of gut microbiota-specific regulatory T cells
Kedmi R. et al. (BioRxiv)
3 dec. 2021
Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury
Li D.K. et al. (BioRxiv)
4 dec. 2021
Tertiary lymphoid structures induced by CXCL13-producing CD4+ T cells increase tumor infiltrating CD8+ T cells and B cells in ovarian cancer
Ukita M. et al. (BioRxiv)
1 jan. 2022
Structurally and functionally distinct early antibody responses predict COVID-19 disease trajectory and mRNA vaccine response
Chakraborty S. et al. (BioRxiv)
3 jan. 2022
Overactive STAT3 drives accumulation of disease-associated CD21low B cells
Masle-Farquhar E. et al. (BioRxiv)
4 jan. 2022
IFN-γ-independent control of M. tuberculosis requires CD4 T cell-derived GM-CSF and activation of HIF-1α
Van Dis E. et al. (BioRxiv)
5 jan. 2022
The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanisms
Willett B.J. et al. (MedRxiv)
1 feb. 2022
Divergent clonal differentiation trajectories of T cell exhaustion
Daniel B. et al. (BioRxiv)
2 feb. 2022
Microenvironmental Sensing by Fibroblasts Controls Macrophage Population Size
Zhou X., Franklin R. et al. (BioRxiv)
1 mars 2022
Pancreas resident macrophage-induced fibrosis has divergent roles in pancreas inflammatory injury and PDAC
Baer J.M. et al. (BioRxiv)
2 mars 2022
Three functionally distinct classes of cGAS proteins in nature revealed by self-DNA-induced interferon responses
Mosallanejad K. et al. (BioRxiv)
3 mars 2022
Germinal center block exacerbates extrafollicular responses and accelerates autoimmune disease progression in a murine lupus model
Voss L.F. et al. (BioRxiv)
1 apr. 2022
Microbial Energy Metabolism Fuels a CSF2-dependent Intestinal Macrophage Niche within Tertiary Lymphoid Organs
Chiaranunt P. et al. (BioRxiv)
2 apr. 2022
Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal anti-tumor immunity
Choi Y. et al. (BioRxiv)
3 apr. 2022
Nuclear envelope disruption triggers hallmarks of aging in lung alveolar macrophages
De Silva N.S. et al. (BioRxiv)
4 apr. 2022
Longitudinal single cell transcriptional and epigenetic mapping of effector, memory, and exhausted CD8 T cells reveals shared biological circuits across distinct cell fates
Giles J.R. et al. (BioRxiv)
5 apr. 2022
The CD58:CD2 axis is co-regulated with PD-L1 via CMTM6 and governs anti-tumor immunity.
Ho P. et al. (BioRxiv)
6 apr. 2022
STING controls T cell memory fitness during infection through T cell intrinsic and IDO dependent mechanisms
Quaney M.J. et al. (BioRxiv)
1 maj 2022
Brain resident memory T cells rapidly expand and initiate neuroinflammatory responses following CNS injury and viral infection
Ayasoufi K. et al. (BioRxiv)
2 maj 2022
Integrated protein and transcriptome high-throughput spatial profiling
Ben-Chetrit N. et al. (BioRxiv)
3 maj 2022
Sex differences in NK cells mediated by the X-linked epigenetic regulator UTX
Cheng M. et al. (BioRxiv)
4 maj 2022
Induction of a CD8 T cell intrinsic DNA damage and repair response is associated with clinical response to PD-1 blockade in uterine cancer
Muroyama Y. et al. (BioRxiv)
5 maj 2022
In Utero Activation of NK Cells in Congenital CMV Infection
Vabeen A.V. et al. (BioRxiv)
6 maj 2022
Distinct gene expression by expanded clones of quiescent memory CD4+ T cells harboring intact latent HIV-1 proviruses
Weymar G.H.J. et al. (BioRxiv)
7 maj 2022
Unaltered T cell responses to common antigens in individuals with Parkinson’s disease
Williams G.P. et al. (BioRxiv)
1 juni 2022
A unique epigenomic landscape defines CD8+ tissue-resident memory T cells
Buquicchio F. et al. (BioRxiv)
2 juni 2022
Terminal differentiation and persistence of effector regulatory T cells essential for the prevention of intestinal inflammation
Dikiy S. et al. (BioRxiv)
3 juni 2022
GATA4 regionalizes intestinal metabolism and barrier function to prevent immunopathology
Earley Z. et al. (BioRxiv)
1 sep. 2022
Long-term retention of antigens in germinal centres is controlled by the spatial organisation of the follicular dendritic cell network
Martinez-Riano A. et al. (BioRxiv)
1 okt. 2022
Release of the pre-assembled naRNA-LL37 composite DAMP re-defines neutrophil extracellular traps (NETs) as intentional DAMP webs
Bork F. et al. (BioRxiv)
2 okt. 2022
Single-cell transcriptomics of resected human traumatic brain injury tissues reveals acute activation of endogenous retroviruses in oligodendrocytes
Garza R. et al. (BioRxiv)
3 okt. 2022
Eradication of tumors with pre-existing antigenic heterogeneity by vaccine-mediated co-engagement of CAR T and endogenous T-cells
Ma Y. et al. (BioRxiv)
1 nov. 2022
Enhanced STAT5a activation rewires exhausted CD8 T cells during chronic stimulation to acquire a hybrid durable effector like state
Beltra J.-C. et al. (BioRxiv)
2 nov. 2022
Cystatin F (Cst7) drives sex-dependent changes in microglia in an amyloid-driven model of Alzheimer’s Disease
Daniels M.J.D. et al. (BioRxiv)
3 nov. 2022
B cell depletion attenuates CD27 signaling of T helper cells in multiple sclerosis
Ulutekin, C. et al. (MedRxiv)
1 jan. 2023
Human intestinal epithelial cells can internalize luminal fungi via LC3-associated phagocytosis
Cohen-Kedar, S. et al. (BioRxiv)
2 jan. 2023
Immunogenicity of non-canonical HLA-I tumor ligands identified through proteogenomics
Lozano-Rabella, M. et al. (BioRxiv)
2 jan. 2023
Differentiation of a CD4+/CD8ab+ Double Positive T cell Population From the CD8 Pool is Sufficient To mediate Graft-vs-Host Disease but not Graft-vs-Leukemia Effects
Hess et al. (BioRxiv)
3 jan. 2023
Human T follicular helper clones seed the germinal center-resident regulatory pool
Le Coz C. et al. (BioRxiv)
4 jan. 2023
The maternal microbiome regulates infant respiratory disease susceptibility via intestinal Flt3L expression and plasmacyoid dendritic cell haematopoiesis
Sikder M.A.A. et al. (BioRxiv)
5 jan. 2023
Synthetic STING agonists elicit powerful vaccine adjuvancy providing robust central memory and anti-tumor effects
Towner et al. (BioRxiv)
1 feb. 2023
A conserved family of immune effectors cleaves cellular ATP upon viral infection
Rousset, F et al. (BioRxiv)
2 feb. 2023
Sexual dimorphism in obesity is governed by RELMα regulation of adipose macrophages and eosinophils
Li, J. et al. (BioRxiv)
3 feb. 2023
A Distinct Phenotype of Polarized Memory B Cell holds IgE Memory
Koenig, J. et al. (BioRxiv)
4 feb. 2023
A Novel MHC-Independent Mechanism of Tumor Cell Killing by CD8+ T Cells
Lerner*, Woroniecka* et al. (BioRxiv).
5 feb. 2023
Tregs constrain CD8+ T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy
Palmeri J.R. et al. (BioRxiv)
1 mars 2023
Unstable EBV latency drives inflammation in multiple sclerosis patient derived spontaneous B cells
Soldan S. et al. (Research Square)
2 mars 2023
Antigen-presenting type-I conventional dendritic cells facilitate curative checkpoint blockade immunotherapy in pancreatic cancer
Mahadevan K.K. et al. (BioRxiv)
1 apr. 2023
Perforin-2 is a pore-forming effector of endocytic escape in cross-presenting dendritic cells
Rodríguez-Silvestre et al. (BioRxiv)
2 apr. 2023
Glioblastoma induces the recruitment and differentiation of hybrid neutrophils from skull bone marrow
Lad BM et al. (BioRxiv)
1 maj 2023
Universal recording of cell-cell contacts in vivo for interaction-based transcriptomics
Nakandakari-Higa et al. (BioRxiv)
2 maj 2023
Group 2 innate lymphoid cells constrain type 3/17 lymphocytes in shared stromal niches to restrict liver fibrosis
Sbierski-Kind*, Cautivo* et al. (Biorxiv)
3 maj 2023
Pannexin-1 channels promote CD8+ T cell effector and memory responses through distinct intracellular pathways
Trupti Vardam-Kaur et al. (BioRxiv)
1 juni 2023
T:B cell communication in ectopic lymphoid follicles in CNS autoimmunity
Kolz A. et al. (BioRxiv)
2 juni 2023
Memory Th1 cells modulate heterologous diseases through innate function.
Rakebrandt*, Yassini* et al. (BioRxiv)
3 juni 2023
Homeostatic, repertoire and transcriptional relationships between colon T regulatory cell subsets.
Ramanan D. et al. (BioRxiv)
1 sep. 2023
The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program
Burton O*, Bricard O* et al. (BioRxiv)
2 sep. 2023
Temporal profiling of human lymphoid tissues reveals coordinated defence to viral challenge
Coates M.L. et al. (BioRxiv)
3 sep. 2023
Human inborn errors of long-chain fatty acid oxidation show impaired inflammatory responses to TLR4-ligand LPS
Mosegaard S. et al. (BioRxiv)
4 sep. 2023
HIF-1α-mediated mitochondrial-glycolytic reprogramming controls the transition of precursor to terminally exhausted T cells
Wu et al. (BioRxiv)
1 okt. 2023
Bacterial Sphingolipids Exacerbate Colitis by Inhibiting ILC3-derived IL-22 Production
Bao, B. et al. (BioRxiv)
2 okt. 2023
TAPIR: a T-cell receptor language model for predicting rare and novel targets.
3 okt. 2023
Adipocytes regulate fibroblast function, and their loss contributes to fibroblast dysfunction in inflammatory diseases
Faust H. et al. (bioRxiv)
