Latest Preprints

1 apr. 2026

CRISPR screens identify targets to rescue age-related T cell dysfunction in cancer

Chen et al. (BioRxiv)

DOI: 10.64898/2026.01.22.701075

CRISPR screens identify targets to rescue age-related T cell dysfunction in cancer

26 mars 2026

Gut microbial composition modulates food-specific CD4+ T cells in food allergy

Weingarden et al. (BioRxiv). DOI: 10.1101/2025.10.27.684919

26 mars 2026

IFNγ-induced IRF1 synergizes with TLR7 signals to tune the IRF4-IRF8 axis and drive pathogenic effector B cell fate

Owiredu et al. (BioRxiv)

DOI: 10.64898/2026.02.06.704376

IFNγ-induced IRF1 synergizes with TLR7 signals to tune the IRF4-IRF8 axis and drive pathogenic effector B cell fate

26 mars 2026

Differentiation of human T follicular helper cells in vitro requires co-operation between STAT3 and SMAD signalling cytokines that is restrained by IL-2

William S. Foster et al., (BioRxiv) DOI 10.1101/2025.01.12.632620

26 mars 2026

CD4 memory T cells orchestrate therapy-responsive immune niches in colorectal cancer liver metastases

Mayoux, et al (BioRxiv) DOI 10.1101/2025.08.22.671704

26 mars 2026

IFNAR1⁺ Neutrophils Orchestrate Chronic Inflammatory Damage Through Mitochondrial Remodeling

Pessoa et al. (BioRxiv) DOI: 10.1101/2025.09.22.677957

26 mars 2026

PD-1 blockade during T cell priming enhances long-term protection against metastatic tumors by epigenetically tuning T cell exhaustion

Dinter et al. (BioRxiv) DOI 10.1101/2025.11.25.690601

26 mars 2026

Chronic sensing of host-derived lipids is an all-in-one signal that primes and activates NLRP3

Dufies et al. (BioRxiv) DOI: 10.1101/2025.10.29.685328

24 mars 2026

Harnessing Inflammatory Monocytes to Overcome Resistance to Anti-PD-1 Immunotherapy

Zimmerman et al. BioRxiv DOI: 10.64898/2026.02.05.704029

17 mars 2026

Antibody Fc receptor CD16a mediates natural killer cell activation via mechanotransduction of piconewton forces

Ma et al. bioRxiv

doi:10.1101/2020.01.28.923011

Antibody Fc receptor CD16a mediates natural killer cell activation via mechanotransduction of piconewton forces

18 feb. 2026

NR4A1 Limits CD8+ T-Cell Effector Responses and Protection in Tuberculosis

Fatima et al. (bioRxiv). DOI: 10.64898/2026.01.12.699051

18 feb. 2026

Immune cells adapt to distinct stem cell niches to govern tissue homeostasis

Parigi SM et al. (BioRxiv)

DOI: 10.64898/2026.01.28.701831

Immune cells adapt to distinct stem cell niches to govern tissue homeostasis

16 feb. 2026

Immune checkpoint inhibitors amplify type 2 immune mediated repair by pro-regenerative scaffolds

Garcia et al. (BioRxiv)

DOI: 10.64898/2026.01.31.703034

Immune checkpoint inhibitors amplify type 2 immune mediated repair by pro-regenerative scaffolds

30 jan. 2026

O-GlcNAcylation drives macrophage IL-4 responsiveness and tissue residency through metabolic and cell cycle calibration

Heieis et al. (BioRxiv)

DOI: 10.64898/2026.01.05.697622

O-GlcNAcylation drives macrophage IL-4 responsiveness and tissue residency through metabolic and cell cycle calibration

30 jan. 2026

Timing of immune checkpoint blockade shapes anti-tumor immunity via a clock-dependent chemokine axis

Lichterman et al. (BioRxiv)

DOI: 10.1101/2025.11.03.686293v1

Timing of immune checkpoint blockade shapes anti-tumor immunity via a clock-dependent chemokine axis

26 jan. 2026

The spatial landscape of infectious mononucleosis tonsils

Leahy CI et al. (BioRxiv)

DOI: 10.1101/2025.10.09.681345

The spatial landscape of infectious mononucleosis tonsils

26 jan. 2026

Discovery of Type I Interferonopathy features in ATR-X Syndrome reveals a non-cannonical role for cGAS in transcriptional regulation.

El-Daher et al., (BioRxiv), DOI: 10.1101/2025.11.19.685761

22 jan. 2026

Chronic alcohol consumption drives inflammaging and transposon derepression in hematopoietic stem and progenitor cells

Yuda et al. BioRxiv DOI: 10.64898/2025.12.25.696246

7 jan. 2026

Access to germinal center IL-4 microniches drives tissue-divergence of IgE memory responses

Villazala-Merino, Sergio et al. (BioRxiv) DOI:10.64898/2025.12.03.692086

7 jan. 2026

Sensory neuronal mTORC1 signaling establishes neuroimmune memory that initiates allergic immunity

Zhu et al. (BioRxiv) doi: 10.1101/2025.11.10.687723

15 dec. 2025

Antigen reactivity defines tissue-resident memory and exhausted T cells in tumours

Thomas N. Burn et al., BioRxiv 10.1101/2025.07.23.666465

12 dec. 2025

Cross-competition shapes CD8+ T cell hierarchies and differentiation after RNA vaccination

McCarron et al. (BioRxiv)

DOI: 10.1101/2025.10.26.684631

Cross-competition shapes CD8+ T cell hierarchies and differentiation after RNA vaccination

10 dec. 2025

Antibody feedback establishes an affinity brake in the germinal center

Yan, Y., et al., (2025). bioRxiv. https://doi.org/10.1101/2025.11.13.688298

3 dec. 2025

Escherichia coli-induced gut IL-33 release inhibits lung type 2 allergic responses

Selgado et al. (BioRxiv) DOI: 10.1101/2025.11.07.687219

28 nov. 2025

Type I interferon signaling instills divergent metastatic phenotypes and immunotherapy responses

Breuer et al. (BioRxiv) DOI: 10.1101/2025.09.18.677123

24 nov. 2025

Somatic TYK2 activating mutations in tumor-infiltrating T cells promote anti-cancer immunity

Li, Z et al. (BioRxiv)

DOI:10.1101/2025.10.13.682217

Somatic TYK2 activating mutations in tumor-infiltrating T cells promote anti-cancer immunity

24 nov. 2025

Precision targeting of autoreactive B cells in systemic lupus erythematosus using anti-9G4 idiotope synthetic immune receptor T cells

Liu, J. et al (BioRxiv)

DOI:10.1101/2025.10.19.682634

Precision targeting of autoreactive B cells in systemic lupus erythematosus using anti-9G4 idiotope synthetic immune receptor T cells

19 nov. 2025

Lactate Blocks Tertiary Lymphoid Structure Formation by Inhibiting B Cell Chemotaxis

Victoire Boulat et al. (BioRxiv)

DOI: 10.1101/2025.08.30.673054

Lactate Blocks Tertiary Lymphoid Structure Formation by Inhibiting B Cell Chemotaxis

5 nov. 2025

Finding the sweet spot: local Treg loss reprograms systemic antitumor immunity without breaking tolerance

Bockman et al. (BioRxiv) DOI: 10.1101/2025.06.26.661765

29 okt. 2025

Endogenous retroelements promote tolerance to dietary antigens

Rivera C.A. et al. (BioRxiv)

DOI: 10.1101/2025.09.09.675192

Endogenous retroelements promote tolerance to dietary antigens

27 okt. 2025

Serpine1 plays a critical role in Th17 cell differentiation and psoriasis pathogenesis

K. Saimaier et al. (BioRxiv) DOI: 2025.05.08.652800

27 okt. 2025

RORγt+ APCs require a distinct cis-regulatory element to instruct tolerance to dietary antigens

Zhao et al. (ResearchSquare) DOI: 10.21203/rs.3.rs-4865841/v1

25 okt. 2025

Brain-Engrafted Monocyte-derived Macrophages from Blood and Skull-Bone Marrow Exhibit Distinct Identities from Microglia

Du et al. (BioRxiv) DOI: 10.1101/2024.08.08.606900

23 okt. 2025

Single cell proteomic analysis defines discrete neutrophil functional states in human glioblastoma

Sadiku & Brenes et al. (BioRxiv)

DOI: 10.1101/2025.07.23.666094

Single cell proteomic analysis defines discrete neutrophil functional states in human glioblastoma

8 okt. 2025

STAT3 operates as an inflammation-dependent transcriptional switch

Simon Grassmann, et al. BioRxiv

DOI: 10.1101/2025.09.26.678857

STAT3 operates as an inflammation-dependent transcriptional switch

24 sep. 2025

The gut microbiota directs vitamin A flux to regulate intestinal T cell development

Srinivasan, T. et al. (bioRxiv) https://doi.org/10.1101/2025.09.08.674524

14 juli 2025

Mapping the nanoscale organization of the human cell surface proteome reveals new functional associations and surface antigen clusters

Floyd et al. (BioRxiv)

DOI: 10.1101/2025.02.12.637979

Mapping the nanoscale organization of the human cell surface proteome reveals new functional associations and surface antigen clusters

29 juni 2025

Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis

Sánchez-Martínez et al. (BioRxiv)

DOI: 2025.02.17.638013v1

Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis

27 juni 2025

Likely circulation of a coronavirus in roe deer populations suggested by SARS-CoV-2 serological investigation in France

Perez et al. (BioRxiv)

DOI: 10.1101/2025.02.19.639030

Likely circulation of a coronavirus in roe deer populations suggested by SARS-CoV-2 serological investigation in France

26 juni 2025

The immunometabolic topography of tuberculosis granulomas governs cellular organization and bacterial control

McCaffrey, E.F. & Delmastro, A.C. et al. (BioRxiv)

DOI: 10.1101/2025.02.18.638923

The immunometabolic topography of tuberculosis granulomas governs cellular organization and bacterial control

20 juni 2025

Control of Inflammatory Response by Tissue Microenvironment

Wu et al. (BioRxiv)

DOI: 10.1101/2024.05.10.592432

Control of Inflammatory Response by Tissue Microenvironment

11 juni 2025

Submicron-Sampling of Living Cells by Macrophages

Fan et al. (BioRxiv)

DOI: 10.1101/2025.04.10.648051

Submicron-Sampling of Living Cells by Macrophages

22 maj 2025

A microenvironment-driven, HLA-II-associated insulin neoantigen elicits persistent memory T cell activation in diabetes

Srivastava et al. (BioRxiv)

DOI:10.1101/2024.11.07.622538

A microenvironment-driven, HLA-II-associated insulin neoantigen elicits persistent memory T cell activation in diabetes

20 maj 2025

Niche Macrophages Recycle Iron to Tumor Cells and Foster Erythroblast Mimicry to Promote Bone Metastasis and Anemia

Han et al. (BioRxiv)

DOI: 10.1101/2025.04.23.650120

Niche Macrophages Recycle Iron to Tumor Cells and Foster Erythroblast Mimicry to Promote Bone Metastasis and Anemia

18 maj 2025

IL-25-induced memory ILC2s mediate long-term small intestinal adaptation

Cortez et al. (BioRxiv)

DOI: 10.1101/2025.03.25.645270

IL-25-induced memory ILC2s mediate long-term small intestinal adaptation

16 maj 2025

A pan-cancer atlas of T cell targets

Li, G. et al (BioRxiv)

DOI: 10.1101/2025.01.22.634237

26 apr. 2025

Neoantigens drive adoptively transferred CD8 T cells to long-lived effectors mediated by lymph node trafficking

Wittling et al. (BioRxiv)

DOI:10.1101/2025.04.18.649565

Neoantigens drive adoptively transferred CD8 T cells to long-lived effectors mediated by lymph node trafficking

22 apr. 2025

Maternal immune activation imprints a regulatory T cell deficiency in offspring that drives an autism-like phenotype

Ellul et al. (BioRixv)

DOI: 10.1101/2025.01.06.631430

Maternal immune activation imprints a regulatory T cell deficiency in offspring that drives an autism-like phenotype

18 apr. 2025

The phagosome-mediated anti-bacterial immunity is governed by the proton-activated chloride channel in peritoneal macrophages

Cheng et al. (BioRxiv)

DOI: 10.1101/2025.02.27.640612

The phagosome-mediated anti-bacterial immunity is governed by the proton-activated chloride channel in peritoneal macrophages

11 apr. 2025

Functional memory T cells are derived from exhausted clones and expanded by checkpoint blockade

Raposo, C.J. et al. (BioRxiv)

DOI: 10.1101/2025.02.10.637523

Functional memory T cells are derived from exhausted clones and expanded by checkpoint blockade

8 apr. 2025

Poxvirus attack of anti-viral defense pathways unleashes an effector-triggered NF-κB response

BC Remick et al. (BioRxiv)

DOI: 10.1101/2025.03.04.641538

Poxvirus attack of anti-viral defense pathways unleashes an effector-triggered NF-κB response

6 apr. 2025

Androgen Signaling in Type 2 Innate Lymphoid Cells Drives Sex Differences in Helicobacter-Induced Gastric Inflammation and Atroph

Duncan et al. (BioRxiv)

DOI:10.1101/2025.03.14.643321

Androgen Signaling in Type 2 Innate Lymphoid Cells Drives Sex Differences in Helicobacter-Induced Gastric Inflammation and Atroph

5 apr. 2025

Monocyte control of organismal energy homeostasis

Martins*, Blankehaus* et al. (BioRxiv)

DOI:10.1101/2025.02.20.639373

Monocyte control of organismal energy homeostasis

27 mars 2025

CDKN2ALow cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance.

Buj et al. (BioRxiv)

DOI: 10.1101/2025.02.08.637227

CDKN2ALow cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance.

17 mars 2025

Tumor-associated macrophages enhance tumor innervation and spinal cord repair

Dolci et al. (BioRxiv)

DOI:10.1101/2024.12.19.629374

Tumor-associated macrophages enhance tumor innervation and spinal cord repair

14 mars 2025

Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19

Maguire et al. (BioRxiv)

DOI: 10.1101/2024.11.14.622799

Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19

12 mars 2025

Lymph nodes link sex-biased immune aging to compromised antigen recognition

Menzel et al. (BioRxiv)

DOI: 10.1101/2025.02.11.637693

Lymph nodes link sex-biased immune aging to compromised antigen recognition

10 mars 2025

Type 1 interferons induced upon respiratory viral infection impair lung metastatic initiation

Farais et al. (BioRxiv)

DOI: 10.1101/2024.12.23.630113

Type 1 interferons induced upon respiratory viral infection impair lung metastatic initiation

27 feb. 2025

Tumor-associated macrophages enhance tumor innervation and spinal cord repair

Dolci et al. (BioRxiv)

DOI: 10.1101/2024.12.19.629374

20 feb. 2025

Resident Tissue Macrophages Govern Intraocular Pressure Homeostasis

Liu et al. (BioRxiv)

DOI: 10.1101/2025.01.25.634888

Resident Tissue Macrophages Govern Intraocular Pressure Homeostasis

10 feb. 2025

Type 1 lymphocytes and interferon-γ accumulate in the thalamus and restrict seizure susceptibility after traumatic brain injury

Mroz et al. (BioRixv)

DOI:10.1101/2024.12.28.630606

Type 1 lymphocytes and interferon-γ accumulate in the thalamus and restrict seizure susceptibility after traumatic brain injury

8 feb. 2025

BLOC1S1 control of vacuolar organelle fidelity modulates TH2 cell immunity and allergy susceptibility

Sharma et al. (BioRxiv)

DOI: 10.1101/2024.03.21.586144

BLOC1S1 control of vacuolar organelle fidelity modulates TH2 cell immunity and allergy susceptibility

31 jan. 2025

Memory-Phenotype Ly49+ CD8 T emerging from the thymus develop into two subsets with distinct immune functions

Laubreton et al. (BioRxiv)

DOI: 10.1101/2024.12.10.627689

Memory-Phenotype Ly49+ CD8 T emerging from the thymus develop into two subsets with distinct immune functions

30 jan. 2025

Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ

Eislmayr et al. (BioRxiv)

DOI:10.1101/2025.01.20.633976

Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ

20 jan. 2025

Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action

Wilhelmsen et al. (BioRxiv)

DOI: 10.1101/2024.12.21.629867

Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action

17 jan. 2025

IL-10 Targets IRFs to Suppress IFN and Inflammatory Response Genes by Epigenetic Mechanisms

Bikash Mishra et al. (BioRxiv)

DOI: 10.1101/2024.11.07.622491

IL-10 Targets IRFs to Suppress IFN and Inflammatory Response Genes by Epigenetic Mechanisms

15 jan. 2025

Lymph Node Fibroblast Phenotypes and Immune Crosstalk Regulated by Podoplanin Activity

Makris et al. (BioRxiv)

DOI: 10.1101/2022.12.01.518753

Lymph Node Fibroblast Phenotypes and Immune Crosstalk Regulated by Podoplanin Activity

20 dec. 2024

Dietary Restriction Enhances CD8⁺ T Cell Ketolysis to Limit Exhaustion and Boost Anti-Tumor Immunity

Oswald B.M. et al. (BioRxiv)

DOI: 10.1101/2024.11.14.621733

Dietary Restriction Enhances CD8⁺ T Cell Ketolysis to Limit Exhaustion and Boost Anti-Tumor Immunity

17 dec. 2024

Early life RSV infection as a preventable risk factor for asthma

De Leeuw et al. (Research Square)

DOI: 10.21203/rs.3.rs-5366915

Early life RSV infection as a preventable risk factor for asthma

15 dec. 2024

Interferon Epsilon Protects Epithelial Barriers from Viral Infection through Autocrine

Casazza et al. (BioRxiv)

DOI: 10.1101/2024.11.15.623843

Interferon Epsilon Protects Epithelial Barriers from Viral Infection through Autocrine

12 dec. 2024

Peptide-MHC-targeted retroviruses enable in vivo expansion and gene delivery to tumor-specific T cells

Xu et al. (BioRxiv)

DOI: 10.1101/2024.09.18.613594

Peptide-MHC-targeted retroviruses enable in vivo expansion and gene delivery to tumor-specific T cells

1 nov. 2024

Immunopeptidomics informs discovery and delivery of Mycobacterium tuberculosis MHC-II antigens for vaccine design

Leddy et al. (BioRxiv)

DOI: 10.1101/2024.10.02.616386

Immunopeptidomics informs discovery and delivery of Mycobacterium tuberculosis MHC-II antigens for vaccine design

23 okt. 2024

Multi-Omics Atlas-Assisted Discovery of Transcription Factors for Selective T Cell State Programming

Kay-Chung et al. (BioRxiv)

DOI:10.1101/2023.01.03.522354

Multi-Omics Atlas-Assisted Discovery of Transcription Factors for Selective T Cell State Programming

15 okt. 2024

A lymphoid tissue chemokine checkpoint prevents loss of CD8+ T cell functionality

Altenburger, LM. et al. (BioRxiv)

DOI: 10.1101/2024.09.19.613830

A lymphoid tissue chemokine checkpoint prevents loss of CD8+ T cell functionality

13 okt. 2024

Microbiota-induced plastic T cells enhance immune control of antigen-sharing tumors

Najar et al. (BioRxiv)

DOI:10.1101/2024.08.12.607605

Microbiota-induced plastic T cells enhance immune control of antigen-sharing tumors

10 okt. 2024

Monocyte-derived cells but not Microglia cause Oxidative Tissue Damage in Neuroinflammation

Villar-Vesga et al. (BioRxiv)

DOI: 10.1101/2024.09.18.612891

Monocyte-derived cells but not Microglia cause Oxidative Tissue Damage in Neuroinflammation

2 okt. 2024

PD-1 controls differentiation, survival, and TCR affinity evolution of stem-like CD8+ T cells

Hor et al. (BioRxiv)

DOI: 10.1101/2024.08.02.606241

PD-1 controls differentiation, survival, and TCR affinity evolution of stem-like CD8+ T cells

1 okt. 2024

Synaptic synergy of T cell receptor and interleukin 2 receptor in CD8+ T cells

Capera et al. (BioRxiv)

DOI: 10.1101/2024.08.13.607831

Synaptic synergy of T cell receptor and interleukin 2 receptor in CD8+ T cells

1 juli 2024

Androgen Signaling Restricts Glutaminolysis to Drive Sex-Specific Th17 Metabolism

Chowdhury et al. (BioRxiv)

DOI: 10.1101/2023.02.10.527741

Androgen Signaling Restricts Glutaminolysis to Drive Sex-Specific Th17 Metabolism

8 maj 2024

Tuft cell IL-17RB restrains IL-25 bioavailability and reveals context-dependent ILC2 hypo proliferation

Feng X et al. (BioRxiv)

DOI: 10.1101/2024.03.04.583299

Tuft cell IL-17RB restrains IL-25 bioavailability and reveals context-dependent ILC2 hypo proliferation

7 maj 2024

Microbiota-derived inosine programs protective CD8+ T cell responses against influenza in newborns

Stevens et al. (BioRxiv)

DOI: 10.1101/2024.04.09.588427

Microbiota-derived inosine programs protective CD8+ T cell responses against influenza in newborns

6 maj 2024

Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or resiratory viral infections

Ngo C. et al. (BioRxiv)

DOI: 10.1101/2024.05.20.594961

Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or resiratory viral infections

5 maj 2024

B cell-mediated antigen presentation promotes adverse cardiac remodeling in chronic heart failure

Lovell et al. (BioRxiv)

DOI: 10.1101/2024.05.08.593153

B cell-mediated antigen presentation promotes adverse cardiac remodeling in chronic heart failure

3 maj 2024

Inhibition of NFAT promotes loss of tissue resident uterine natural killer cells and attendant pregnancy complications in humans

Asiimwe et al. (BioRxiv)

DOI: 10.1101/2024.03.07.583906

Inhibition of NFAT promotes loss of tissue resident uterine natural killer cells and attendant pregnancy complications in humans

2 maj 2024

Epigenetic signature and key transcriptional regulators of human antigen-specific type 1 regulatory T cells

Alma-Martina Cepika, et al. (BioRxiv)

DOI: 10.1101/2024.03.07.582969

Epigenetic signature and key transcriptional regulators of human antigen-specific type 1 regulatory T cells

1 maj 2024

Arp2/3 complex-dependent actin regulation protects the survival of tissue-resident mast cells.

Kaltenbach et al. (BioRxiv)

DOI: 10.1101/2024.02.23.581763

Arp2/3 complex-dependent actin regulation protects the survival of tissue-resident mast cells.

4 apr. 2024

Low Avidity T cells drive endogenous tumor immunity in mice and humans

Singhaviranon et al. (Research Square)

DOI: 10.21203/rs.3.rs-3903457/v1

Low Avidity T cells drive endogenous tumor immunity in mice and humans

3 apr. 2024

Breast Cancer Macrophage Heterogeneity and Self-renewal are Determined by Spatial Localization

Ben-Chetrit et al. (BioRxiv)

DOI: 10.1101/2023.10.24.563749

Breast Cancer Macrophage Heterogeneity and Self-renewal are Determined by Spatial Localization

2 apr. 2024

CD4+ TRM sustain the chronic phase of auto-immune neuroinflammatory disease

Pignata et al. (BioRxiv)

DOI:10.1101/2024.03.26.586880

CD4+ TRM sustain the chronic phase of auto-immune neuroinflammatory disease

1 apr. 2024

Granzyme B-based CAR T cells block metastasis by eliminating circulating tumor cells

Bin Sun, et.al. (BioRxiv)

DOI: 10.1101/2024.03.18.585442

Granzyme B-based CAR T cells block metastasis by eliminating circulating tumor cells

20 mars 2024

CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit

Yi et al. (BioRxiv)

DOI:10.1101/2024.02.26.582108

CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit

2 mars 2024

Interleukin-1 receptor antagonist is a conserved driver of tuberculosis

Kotov. et al. (BioRxiv)

DOI: 10.1101/2023.10.27.564420

Interleukin-1 receptor antagonist is a conserved driver of tuberculosis

1 mars 2024

Opposing effects of pre-existing antibody and memory T cell help on the dynamics of recall germinal centers

Schiepers A. et al. (BioRxiv)

DOI: 10.1101/2023.12.15.571936

Opposing effects of pre-existing antibody and memory T cell help on the dynamics of recall germinal centers

1 mars 2024

CD39 is expressed on functional effector and tissue resident memory CD8+ T cells

Isaacs, JF et al. (BioRxiv)

DOI: 10.1101/2024.03.15.585252v1

CD39 is expressed on functional effector and tissue resident memory CD8+ T cells

4 feb. 2024

Microbiota encoded fatty-acid metabolism expands tuft cells to protect tissues homeostasis during Clostridioides difficile infection in the large intestine

Kellogg et al. (BioRxiv)

DOI: 10.1101/2024.01.29.574039

Microbiota encoded fatty-acid metabolism expands tuft cells to protect tissues homeostasis during Clostridioides difficile infection in the large intestine

3 feb. 2024

Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter.

Di Gioia et al. (BioRxiv)

DOI: 10.1101/2023.11.21.568047

Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter.

2 feb. 2024

Cytotoxic CD4+ T cells in the bone marrow compromise healthy ageing by enhancing granulopoiesis

Enrique Gabamdé-Rodrigez, Gonzalo Soto-Heredero, et al. (BioRxiv)

DOI: 10.1101/2024.01.26.577360

Cytotoxic CD4+ T cells in the bone marrow compromise healthy ageing by enhancing granulopoiesis

1 feb. 2024

IQGAP2 regulates blood-brain barrier immune dynamics

Katdare KA et al. (BioRxiv)

DOI: 10.1101/2023.02.07.527394

IQGAP2 regulates blood-brain barrier immune dynamics

17 jan. 2024

Tuft cell derived acetylcholine is an effector of type 2 immunity and directly targets helminth parasites in the gut lumen.

Ndjim M. et al. (BioRxiv)

DOI: 10.1101/2023.12.08.570757

Tuft cell derived acetylcholine is an effector of type 2 immunity and directly targets helminth parasites in the gut lumen.

3 jan. 2024

Cancer immunotherapy responses persist after lymph node resection

Zhou H et al. (BioRxiv)

DOI: 10.1101/2023.09.19.558262

Cancer immunotherapy responses persist after lymph node resection